In order to build your tolerance, you must take your drops every day. Allergy drops have been shown to significantly decrease allergy symptoms and allergy medication use, as well as to significantly improve allergy-related quality of life. The size of each dose as well as the frequency at which they are administered plays a large role in the degree to which symptoms improve. As such, using the drops sporadically or less than prescribed may result in suboptimal improvement in allergy symptoms.